Skip to main content

Exploring the Link Between Circadian Rhythms, Longevity, and Wearable Data: Insights and Future Directions




A recent study in NHANES 2011–2014 explores the potential connection between disruptions in circadian rhythms, measured using wearable devices, and their impact on health outcomes and longevity.

The study analyzes data from 7,297 U.S. adults collected through wearable accelerometers as a novel digital biomarker for longevity.

Five distinct clusters were identified based on activity profiles: "High activity," "Low activity," "Mild circadian rhythm (CR) disruption," "Severe CR disruption," and "Very low activity."

The findings reveal that young adults with extreme circadian rhythm disturbance exhibit higher white blood cell counts and accelerated biological aging.

Older adults with circadian disruption are associated with increased systemic inflammation indexes, advanced biological aging, and higher all-cause mortality risk.

The research underscores the importance of circadian alignment for longevity at all ages and suggests that wearable accelerometers can help identify at-risk populations and personalize treatments for healthier aging.

The study emphasizes the potential of digital biomarkers in predicting and promoting healthy aging, aligning with the concept of precision medicine. The research also highlights the need to leverage technological advancements, such as smartwatches, to monitor and understand circadian rhythms effectively.

Machine learning techniques and data-driven clustering approaches provide valuable insights for subpopulation identification and precision medicine, enabling interventions tailored to specific health risks.

Source: Shim, J., Fleisch, E. & Barata, F. Wearable-based accelerometer activity profile as digital biomarker of inflammation, biological age, and mortality using hierarchical clustering analysis in NHANES 2011–2014. Sci Rep 13, 9326 (2023). https://doi.org/10.1038/s41598-023-36062-y

The study contributes to the understanding of the association between circadian rhythms and longevity using continuously collected wearable data, expanding the knowledge in the field and providing potential avenues for further research.
Labels:

Comments

Post a Comment

Popular posts from this blog

Guilt-Free Biscuits: A Step-by-Step Guide to Sweetener-Reformulated Treats

Sweetener Reformulated Biscuits: Step-by-Step Recipe Discover a healthier twist on your favorite biscuits with our sweetener reformulated recipe. Perfect for those looking to reduce sugar intake without compromising on taste! Ingredients: Dry Ingredients: 2 cups whole wheat flour 1 tsp baking powder 1/2 tsp salt Wet Ingredients: 1/2 cup unsweetened applesauce 1/4 cup vegetable oil 1/2 cup Stevia or preferred sweetener 1 tsp vanilla extract Instructions: Preheat Oven: Set your oven to 350°F (175°C). Mix Dry Ingredients: In a large bowl, combine flour, baking powder, and salt. Blend Wet Ingredients: In another bowl, mix applesauce, oil, sweetener, and vanilla until smooth. Combine: Gradually add wet ingredients to dry ingredients, stirring until just combined. Shape Dough: Roll out the dough on a floured surface and cut into desired shapes. Bake: Place on a baking sheet and bake for 12-15 minutes or until golden brown. Cool and Enjoy: Let the biscuits cool before serving. More info: ...
Post a Comment
See more...

Brain health. Promising prebiotics and probiotics combination

According to new research, the bacteria in our gut, known as gut microbiota, play an important role in brain injury and healing after a stroke. Taking particular types of prebiotics and probiotics can help with brain injury, inflammation, gut bacteria imbalances, and intestinal health. However, we still don't know whether prebiotics, probiotics, or synbiotics (a combination of both) perform best for particular conditions, or how they operate. In this study, scientists tested a new synbiotic formulation containing multiple strains of probiotics Lactobacillus reuteri UBLRu-87 Lactobacillus plantarum UBLP-40 Lactobacillus rhamnosus UBLR-58 Lactobacillus salivarius UBLS-22 Bifidobacterium breve UBBr-01 and prebiotic fructooligosaccharides (FOS)  FOS are extracted from the blue agave plant and fruits and vegetables such as bananas, onions, chicory root, garlic, asparagus, jícama, and leeks. Some grains and cereals, such as wheat and barley, also contain FOS. The Jerusalem artichoke and ...
Post a Comment
See more...

Catch of the Day: Hypnosis, Fibromyalgia, IBD, Gut Microbiota, Aging

Hypnosis as a Tool for Managing Fibromyalgia Pain "Harnessing Hypnosis: A Promising Approach to Tackle Fibromyalgia Pain" Fibromyalgia syndrome (FMS) is a complex condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and emotional challenges. The exact cause of FMS is not fully understood, but there's evidence suggesting a link between childhood/adulthood abuse or neglect and its development. Treating FMS can be difficult due to its resistance to most treatments. However, a recent review suggests that hypnotherapy, a psychological intervention, could be effective in managing FMS pain. This technique aims to reduce pain, fatigue, sleep problems, anxiety, and depression by using hypnosis to address emotional conflicts and unresolved traumas associated with FMS. This non-invasive approach might offer relief to those struggling with fibromyalgia. De Benedittis G. The Challenge of Fibromyalgia Efficacy of Hypnosis in Alleviating the Invisibl...
Post a Comment
See more...