Wellness-uptodate

  Carbamate and Alzheimer Alzheimer's disease is a brain disorder that mostly affects older people. It gets worse over time and causes problems with memory and thinking. We still don't fully understand why Alzheimer's disease happens, but it seems to be caused by a lot of different things going wrong. There are some important signs that we often see in the brains of people with Alzheimer's. These include the loss of certain brain cells, the buildup of abnormal substances like plaques, problems with metals in the brain, changes in a protein called tau, too much stress inside brain cells, swelling and problems with the immune system in the brain, and issues with the energy centers in brain cells. Current treatments, right now, is based in some medicines that can help with the symptoms of Alzheimer's, but they don't fix the main problems in the brain.  These medicines are called donepezil, rivastigmine, galantamine, and memantine. There's a need for better drug...

  Klotho could hold the key to Alzheimer’s treatment There are over 55 million people living with dementia globally, with 10 million new cases annually, informs WHO. 70 percent is caused by Alzheimer‘s disease, the most common form of dementia. Cognitive impairment is the beginning of dementia processes that appear because of various diseases affecting the brain. Recently, according to a study published in the prestigious journal Nature, the administration of a protein called klotho in elderly primates improved cognitive function. This could lead, according to the UNQ Scientific News Agency, to clinical trials in humans in the medium term. What is Klotho? Klotho is a protein found naturally in the body whose levels decrease with age. The name is from the Greek goddess Clotho, one of the grim reapers who weaves the thread of life. The prestigious American doctor Eric Topol, affirmed that the genetic variants in klotho protect against Alzheimer’s, according to scientific work, throug...