Creatine and post–COVID-19 fatigue syndrome

A small study suggests that taking creatine as a supplement for six months may significantly improve clinical features of post–COVID-19 fatigue syndrome (long COVID).

The study, conducted by researchers from the University of Novi Sad, Serbia, found that creatine supplements led to reduced fatigue and improved scores for various long COVID-related symptoms, such as loss of taste, breathing difficulties, body aches, headaches, and concentration problems.

The study also observed increased creatine levels in the brain and reduced lung and body pain among participants.

However, experts caution that the study's small sample size and the fact that the patients had recent COVID infections make it difficult to generalize the results, and further research is needed to confirm the effectiveness of creatine supplements in treating long COVID. There were no major side effects reported from the creatine supplementation.

Slankamenac, J., Ranisavljev, M., Todorovic, N., Ostojic, J., Stajer, V. and Ostojic, S. M. (2023) Food Science & Nutrition. doi: 10.1002/fsn3.3597. https://onlinelibrary.wiley.com/doi/10.1002/fsn3.3597

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