WUTD Today 5/25/2022 Anxiety. The bar ridiculously low, Metformin, Sick after Exercise, Diet makes a difference

'Set the bar ridiculously low': Rhik Samadder's golden rule for beating anxiety - The Guardian
The Guardian
Apart from CBT, the usual practical stuff works. Nutritious food, regular sleep and exercise; seeing friends, tidying up, doing things I'm good at.

Metformin, Lifestyle Interventions Can Prevent T2D, But Do Little for CVD Risk in Prediabetes
Using 21 years of follow-up data from more than 3000 patients with prediabetes, results of the DPPOS study demonstrate metformin use and lifestyle intervention reduced the risk of progressing to T2D, but did little to reduce the long-term risk of cardiovascular disease in these patients.

Feel Sick After Exercise? A Scientist Explains Why, And How to Prevent It - ScienceAlert
ScienceAlert
Many of us exercise to feel better. While some of us get "runners' highs" after a workout, unfortunately some of us leave the gym feeling nauseous ...

The overlooked variable in animal studies: why diet makes a difference - Nature
Nature
“Standard chow can be so many different things,” says team member Giada De Palma, a microbiome researcher at McMaster University in Hamilton, Canada.

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Light Therapy holds promise as a treatment for Alzheimer's Disease

A new article, conducted by Lili Zang and colleagues from Weifang Medical University School of Nursing in Shandong Province, China, discusses a meta-analysis of 15 high-quality trials that investigated the impact of light therapy on individuals with Alzheimer’s disease (AD). The meta-analysis included 598 patients with mild to moderate Alzheimer’s disease, and it covered 15 randomized controlled trials conducted in seven different countries. Those trials were published between 2005 and 2022. Sleep Improvement Light therapy led to significant improvements in several sleep measures. It notably enhanced sleep efficiency, increased interdaily stability, and reduced intradaily variability, all of which are indicators of better sleep quality. Light therapy was associated with a reduction in agitation, depression, and caregiver burden among individuals with Alzheimer’s disease. A significant advantage over usual care was shown in reducing the severity of psychobehavioral symptoms, as assessed...

Los no fumadores engordan menos

Un nuevo estudio relaciona el tabaquismo con la ganancia de peso, y concluye que las personas fumadoras activas, no sólo las que lo dejan, engordan más que las no fumadoras. Después de cuatro años de análisis en la Universidad de Navarra, las personas que menos engordaron fueron las que nunca habían fumado.

Lacticaseibacillus rhamnosus may help in periodontal disease

A new study explores how a specific probiotic, Lacticaseibacillus rhamnosus GG (LGG), might help improve the regeneration of bones in the gums affected by periodontal disease, especially in the presence of high cholesterol levels (hyperlipidemia). Periodontal disease can lead to the loss of bone in the jaw, making it challenging for the bone to regenerate. The researchers used a rat model with conditions mimicking periodontal disease, high cholesterol, and a defect in the gums. The rats were given LGG for six weeks, and then various measurements were taken after sacrificing the rats to understand the effects. They found that the bone density, volume, and thickness in the affected area increased after the rats were given LGG. Interestingly, these improvements were not due to direct effects on the oral bacteria but were linked to changes in the gut microbiota. When fecal matter containing the altered gut bacteria from LGG-treated rats was transplanted into other rats, si...

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