C. M. Sagasta, M.D. in Medium 10-26-2023. A 2004 study by Shih-Yi Huang and colleagues sheds light on an intriguing aspect of major depressive disorder, specifically the link between hypoalbuminemia and depression. In that research, they compared serum albumin levels in drug-free patients with major depressive disorder to a control group with similar diets. The study found that patients with major depressive disorder had significantly lower serum albumin levels, and the severity of depression was inversely related to albumin levels. Importantly, these findings suggested that hypoalbuminemia in depression is not simply a result of malnutrition. However, the authors stressed the need for more extensive research to confirm these findings. A recent article titled “Association between albumin and depression: a population-based study” by Sabah Al-Marwani and colleagues explores an intriguing connection. Again, the relationship between serum albumin levels and depression in a population...
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