Potential role of MDMA in the treatment of loneliness

Researchers are exploring the potential use of MDMA, commonly known as “ecstasy” or “molly,” as a tool to treat loneliness. Amid concerns about a growing loneliness epidemic, early studies suggest that MDMA could enhance social connectedness and reduce defensiveness.

In a recent small-scale study involving 18 participants, those who took MDMA reported increased feelings of connection during social interactions.

While the study is limited, researchers believe it has implications for MDMA-assisted therapy, particularly in helping patients feel safe and trusting for deeper emotional exploration.

MDMA is currently being investigated for its therapeutic potential and has cleared clinical trials for treating posttraumatic stress disorder (PTSD).

The drug, along with psychedelics like LSD and psilocybin, has been shown to boost social behaviors in both humans and animals. These substances may induce a sense of dissolution of the self-other boundary, leading to increased empathy and social bonding.

Loneliness has been linked to various health risks, including cancer, heart disease, and a shorter lifespan.

Chronic loneliness alters thinking and behavior, making individuals more fearful of social contact.

MDMA-assisted therapies could potentially address these defensive tendencies, helping individuals overcome loneliness in a therapeutic setting.

Despite the promising findings, caution is advised due to potential psychological effects and risks of misuse.

While MDMA and psychedelics are generally considered safe in controlled settings, researchers emphasize the need for professional supervision and clear guidelines.

The exact mechanisms underlying the positive effects of these substances on empathy and social connection are not fully understood, highlighting the challenges and the need for further research.

Source:

Medscape Medical News. MDMA Therapy for Loneliness? Researchers Say It Could Work. Marta Zaraska. December 05, 2023

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