Wellness-uptodate

Carvacrol is a phenolic monoterpenoid found in various essential oils. Oregano, thyme, and bergamot contain carvacrol. It boasts a range of beneficial properties for potential clinical applications. This compound has shown antimicrobial, antioxidant, and anticancer activities. It showed antimicrobial efficacy against food-borne pathogens like Escherichia coli and Salmonella. It is attributed to a unique combination of its chemical characteristics. Carvacrol, often used alongside thymol (another phenolic monoterpenoid found in these oils), exhibits high antioxidant activity and has been employed as a dietary additive to enhance the antioxidant status in animals (I.E. in poultry nutrition) Preclinical studies suggest promising anticancer properties of carvacrol, particularly in breast, liver, and lung carcinomas, through (proapoptotic) mechanisms involving elimination of DNA abnormalities. However, despite a well-defined toxicological profile, the lack of human trials hinders conclusive ...

  A small study suggests that taking creatine as a supplement for six months may significantly improve clinical features of post–COVID-19 fatigue syndrome (long COVID). Those symptoms are: Fatigue Shortness of breath Chest pain Joint pain Cognitive difficulties often referred to as “brain fog.”  The study, conducted by researchers from the University of Novi Sad, Serbia, found that creatine supplements led to reduced fatigue and improved scores for various long COVID-related symptoms, such as loss of taste, breathing difficulties, body aches, headaches, and concentration problems.  Creatine is a natural compound found in small amounts in certain foods and produced by the body, mainly in muscles. It plays a crucial role in the Adenosine Triphosphate -Phosphocreatine (ATP-PC) energy system, which is the primary source of energy for short bursts of intense activities lasting from 1 to 30 seconds, like weightlifting or sprinting. Supplementing with creatine has been proven to...

Researchers are exploring the potential use of MDMA, commonly known as “ecstasy” or “molly,” as a tool to treat loneliness. Amid concerns about a growing loneliness epidemic, early studies suggest that MDMA could enhance social connectedness and reduce defensiveness. In a recent small-scale study involving 18 participants, those who took MDMA reported increased feelings of connection during social interactions. While the study is limited, researchers believe it has implications for MDMA-assisted therapy, particularly in helping patients feel safe and trusting for deeper emotional exploration. MDMA is currently being investigated for its therapeutic potential and has cleared clinical trials for treating posttraumatic stress disorder (PTSD). The drug, along with psychedelics like LSD and psilocybin, has been shown to boost social behaviors in both humans and animals. These substances may induce a sense of dissolution of the self-other boundary, leading to increased empathy and social bon...